A Comparison Between NMN and Reduced Form NMN
NMN and NMNH (Reduced NMN) both belong to the house of NAD+ precursors, one of the scientifically recognized factors impacting the aging process. Due to their function in cellular health energy metabolism and DNA repair, they have been garnering significant attention in the supplement market, especially among health enthusiasts.
Let's delve into the revolutionary potentials of NMNH (Reduced NMN) and its differentiation from NMN.
Abbreviations
To clarify our discussion, let's define the key abbreviations used in this comparison of NMNH and NMN:
NMNH: Reduced Nicotinamide Mononucleotide
NMN: Nicotinamide Mononucleotide
NAD+: Nicotinamide Adenine Dinucleotide
NR: Nicotinamide Riboside
NMNH
NMNH (Reduced NMN) or dihydronicotinamide mononucleotide, stands for Reduced Nicotinamide Mononucleotide.
Studies in animal models suggest that NMNH (Reduced NMN) has the potential to rapidly and significantly increase NAD levels, surpassing NMN or NR, presenting an exciting avenue for NAD replenishment.
NMN
NMN is called Nicotinamide Mononucleotide and is a NAD+ booster with proven benefits.
NMN acts as a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a critical coenzyme involved in energy production, DNA repair, and cellular regulation.
NMNH: Impacting NAD+ in Ways Like Never Before
Research indicates that NMNH is potentially more effective than NMN in boosting NAD+ levels. A study* published in the prestigious journal of the Federation of American Societies for Experimental Biology (FASEB) has shed light on NMNH's remarkable attributes:
10X NAD+ Surge
NMNH (Reduced NMN) takes the concept of NAD+ enhancement to new heights. In a head-to-head comparison, NMNH exhibited exceptional potency compared to Nicotinamide Mononucleotide (NMN). NMNH demonstrated a nearly 10-fold increase in cellular NAD+ levels, showcasing its remarkable efficacy.
24 Hrs Steady NAD+ Increase
The dynamics of NMNH (Reduced NMN) are captivating. Upon supplementation, NMNH rapidly elevated NAD+ levels within just 15 minutes at an unprecedented pace. What sets NMNH apart is its ability to sustain this elevation, with NAD+ levels remaining 2-fold for up to 24 hours. This contrasts sharply with the quick plateau observed with NMN.
Multi-Tissue NAD+ Influence, 5 Organs
NMNH (Reduced NMN)'s impact reverberates across various tissues. Notably, NMNH triggered significant increases in NAD+ levels within vital organs such as the liver and kidney, signaling its potential for comprehensive cellular support. The brain, muscle, brown adipose tissue, and heart—all critical hubs of biological activity—also experienced heightened NAD+ levels, a feat not replicated by NMN.
NMNH V.S. NMN (NAD+ Rise)
Our clinical studies have revealed a striking finding: the NAD+ increase triggered by NMNH (Reduced NMN) is five times greater than that achieved by NMN. This substantial difference is a clear testament to NMNH's superior efficacy in boosting cellular NAD+ levels.
While our current research underscores the promising benefits of NMNH, it's important to note that we are still investigating its full safety profile.
NMNH V.S. NMN (Multi-Tissue NAD+ Rise)
NMNH stands out for its efficiency in boosting NAD+ levels, requiring only one-tenth the dosage compared to NMN to achieve comparable results. This efficiency signifies a significant advancement in NAD+ supplementation, as it suggests that smaller amounts of NMNH can deliver the same beneficial increase in NAD+ levels that NMN provides, but with reduced dosage requirements. This not only makes NMNH a more potent option but also potentially enhances its appeal and usability for consumers seeking effective NAD+ enhancement solutions.
Comparison Between NMNH and NMN
When comparing NMNH and NMN, several key differences emerge:
Molecular and Chemical Composition
The molecular structure and chemical composition of NMNH and NMN are fundamentally different. NMNH is a reduced form of NMN, a modification that significantly enhances its ability to raise NAD+ levels in the body. This structural difference is key to NMNH's enhanced efficacy, enabling more efficient cellular uptake and utilization, which in turn contributes to more effective NAD+ replenishment.
Health Implications
The impact of NMNH on health appears to be more extensive and potent compared to NMN. NMNH's capability to influence multiple tissues and sustain NAD+ boosting points to its potential for offering comprehensive health benefits. Particularly in the realms of anti-aging and cellular health, NMNH's multifaceted influence suggests that it could be more effective in combating age-related decline and supporting cellular functions across a wider array of body tissues.
NAD+ Level Rise
Empirical evidence indicates that NMNH induces a significantly higher and more prolonged increase in NAD+ levels when compared to NMN. This difference is crucial, as NAD+ is a vital coenzyme that plays a central role in metabolic processes, DNA repair, and energy production. The heightened and sustained elevation of NAD+ levels by NMNH could translate into more pronounced health benefits, including better cellular energy production and enhanced repair and maintenance of cellular components.
Dosage Considerations
Both NMNH and NMN are undergoing extensive testing to determine their optimal dosages. NMNH's enhanced potency potentially allows for lower dosage requirements compared to NMN, which can directly impact the end-consumer experience. A smaller dosage of NMNH means that supplements can be produced in smaller capsules or tablets, making them more convenient and appealing for daily consumption. This precise dosage determination is crucial for guiding the practical application of health supplements and treatments, ensuring users receive effective, manageable, and consumer-friendly options for their wellness routines.
NMNH (Reduced NMN) has demonstrated the potential to surpass conventional NAD+ precursors in terms of efficacy in cellular health enhancement. Learn how we ensure the ultimate safety and efficacy through the UthPeak™ preclinical and clinical trials and studies.